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EurekAlert! - Medicine and Health

11/20/2018 12:00 AM
Live probiotics can re-balance the gut microbiome and modify immune system response
(Cello Health PR) New research published in the International Journal of Pharmaceutics demonstrates that 'good' bacteria in the live probiotic SymproveTM can successfully reach and colonise the gut, where they go on to change the existing gut flora. They are also capable of modifying immune response.

11/20/2018 12:00 AM
Abramson Cancer Center joins National Comprehensive Cancer Network
(University of Pennsylvania School of Medicine) The Abramson Cancer Center at the University of Pennsylvania announced today that it is joining the National Comprehensive Cancer Network® as its 28th member institution.

11/20/2018 12:00 AM
Frogs breed young to beat virus
(University of Exeter) Frogs from groups exposed to a deadly virus are breeding at younger ages, new research suggests.

11/20/2018 12:00 AM
Many patients diagnosed with adenomas may not receive colonoscopies in recommended time frame
(American Association for Cancer Research) Patients who are diagnosed with adenomas, a possible precursor of colorectal cancer, often do not receive subsequent colonoscopies within the recommended time frame.

11/20/2018 12:00 AM
Improving dementia care and treatment saves thousands of pounds in care homes
(University of Exeter) Improving staff training in care homes and reducing reliance on harmful medications saves thousands of pounds per year, as well as improving quality of life and reducing agitation in dementia, new research has demonstrated.

11/19/2018 12:00 AM
Proposed cancer treatment may boost lung cancer stem cells, study warns
(Boston Children's Hospital) Epigenetic therapies -- targeting enzymes that alter what genes are turned on or off in a cell -- are of growing interest in the cancer field as a way of making a cancer less aggressive or less malignant. Researchers at Boston Children's Hospital now report that at least one epigenetic therapy that initially looked promising for lung cancer actually has the opposite effect, boosting cancer stem cells that are believed to drive tumors.

11/19/2018 12:00 AM
Cessation fatigue predicts which smokers making a quit attempt are likely to relapse
(Medical University of South Carolina) Cessation fatigue increased in the first six weeks of a quit attempt and increased the likelihood of relapse, report researchers at the Medical University of South Carolina in the Journal of Consulting and Clinical Psychology. Higher cessation fatigue also predicted worse performance on several other important cessation milestones. Cessation fatigue offers a new target for treatment interventions, using either existing pharmacological therapies or mobile Health technologies designed to reduce the stress of a quit attempt.

11/19/2018 12:00 AM
'Druggable' cancer target found in pathway regulating organ size
(Boston Children's Hospital) It's known that cancer involves unchecked cell growth and that a biological pathway that regulates organ size, known at the Hippo pathway, is also involved in cancer. It's further known that a major player in this pathway, YAP, drives many types of tumors. Now, researchers at Boston Children's Hospital have solved an ongoing problem: how to turn this knowledge into a practical drug target.

11/19/2018 12:00 AM
Human images from world's first total-body scanner unveiled
(University of California - Davis) EXPLORER, the world's first medical imaging scanner that can capture a 3D picture of the whole human body at once, has produced its first scans.

11/19/2018 12:00 AM
Using Skype to beat the blues
(Oregon Health & Science University) Researchers compared four different types of online communication technologies -- video chat, email, social networks and instant messaging -- used by people 60 and older and then gauged their symptoms of depression based on survey responses two years later. The study found that people who used video chat functions such as Skype and FaceTime had almost half the estimated probability of depressive symptoms compared with older adults who did not use any communication technologies.

11/19/2018 12:00 AM
Study links shoulder ultrasound brightness with type 2 diabetes
(Henry Ford Health System) Henry Ford Hospital researchers may have unknowingly happened on a new predictor of type 2 diabetes as part of a new ultrasound shoulder study. The predictor may be an ultrasound of the deltoid muscle, which researchers found appears much brighter on diabetic patients than on obese nondiabetic patients.

11/19/2018 12:00 AM
Ohio University research into obesity-stopping protein receives NIH funding
(Ohio University) A research project headed by a faculty member from the Ohio University Heritage College of Osteopathic Medicine has received $464,145 in funding from the National Institutes of Health.

11/19/2018 12:00 AM
To resolve inflammation, location matters
(University of Pennsylvania) A single protein can both restrain the initiation of inflammation and help to actively resolve it, according to new research led by George Hajishengallis of the University of Pennsylvania and Triantafyllos Chavakis of Technical University of Dresden. They found that the type of cell that secretes the protein determines which activity the protein promotes.

11/19/2018 12:00 AM
Researchers find multisystem disorder caused by CCDC47 variants
(Clinic for Special Children) Researchers and clinicians through a multicenter collaboration have identified a novel multisystem disorder caused by bi-allelic variants in the CCDC47 gene. Their findings are reported in the American Journal of Human Genetics. In this study, detailed clinical characterization and functional studies were performed on four unrelated individuals with a complex multisystem disorder characterized by woolly hair, liver dysfunction, itchy skin, unusual facial features, low muscle tone, and global developmental delay.

11/19/2018 12:00 AM
Freeze-frame microscopy captures molecule's 'lock-and-load' on DNA
(University of California - Berkeley) One of the body's largest macromolecules is the machinery that gloms onto DNA and transcribes it into mRNA, the blueprint for proteins. But the molecule, TFIID, is complex with lots of floppy appendages, which makes it hard to obtain a clear picture of its structure. Using state-of-the-art cryo-electron microscopy detectors and computer analysis, UC Berkeley scientists have captured unprecedented detail of how TFIID's structure changes as it binds to DNA and recruits other proteins.

11/19/2018 12:00 AM
Mount Sinai researchers study second-hand marijuana smoke in children
(The Mount Sinai Hospital / Mount Sinai School of Medicine) In a study designed to evaluate second-hand marijuana smoke exposure among children -- a topic that scientists have not yet widely addressed -- researchers at the Icahn School of Medicine at Mount Sinai found that nearly half of children whose parents smoked marijuana showed evidence of second-hand marijuana smoke exposure. The study appears in the December issue of Pediatrics.

11/19/2018 12:00 AM
Research offers hope for simpler cancer diagnosis and treatment
(Brigham Young University) Imagine: No more biopsies. No more spinal taps. With help from recent research, cancer patients may be instead eventually be able to take a simple blood test to diagnose, monitor and tailor appropriate therapies.

11/19/2018 12:00 AM
Response to daily stressors could affect brain health in older adults
(Oregon State University) Taking typical daily annoyances such as a long wait at the doctor's office or a traffic jam on the freeway in stride may help preserve brain health in older adults.

11/19/2018 12:00 AM
Novel target identified for neuron regeneration, functional recovery in spinal cord injury
(Temple University Health System) Restoring the ability to walk following spinal cord injury (SCI) requires neurons in the brain to reestablish communication pathways with neurons in the spinal cord. Mature neurons, however, are unable to regenerate their axons to facilitate this process. Now, Temple scientists show that this limitation may be overcome by targeting liver kinase B1 (LKB1) protein. In mice with SCI, targeted LKB1 upregulation stimulated long-distance neuron regeneration, leading to gains in functional recovery.

11/19/2018 12:00 AM
Scientists trained a computer to classify breast cancer tumors
(UNC Lineberger Comprehensive Cancer Center) In a study published in the journal NPJ Breast Cancer, researchers reported they used a form of artificial intelligence called machine learning, or deep learning, to train a computer to identify certain features of breast cancer tumors from images.

11/19/2018 12:00 AM
Researchers offer perspective on legal, ethical implications of lost eggs and embryos
(Brown University) Three medical and legal scholars discussed the implications of one couple's wrongful death suit seeking compensation for the March 2018 loss at a fertility center of more than 4,000 frozen eggs and embryos.

11/19/2018 12:00 AM
Screening tool is effective for identifying child sex trafficking victims in a pediatric ED
(Society for Academic Emergency Medicine) An initial screening tool can be used effectively in a busy, inner?city emergency department to identify child sex trafficking victims presenting with high?risk health complaints.

11/19/2018 12:00 AM
A major step toward non-viral ocular gene therapy using laser and nanotechnology
(Polytechnique Montréal) Gold nanoparticles, which act like 'nanolenses,' concentrate the energy produced by the extremely short pulse of a femtosecond laser to create a nanoscale incision on the surface of the eye's retina cells. This technology, which preserves cell integrity, can be used to effectively inject drugs or genes into specific areas of the eye, offering new hope to people with glaucoma, retinitis or macular degeneration.

11/19/2018 12:00 AM
Widely used reference for the human genome is missing 300 million bits of DNA
(Johns Hopkins Medicine) Experts say additional reference genomes from different populations are needed for research.

11/19/2018 12:00 AM
Study: In-person, but not online, social contact may protect against psychiatric disorders
(Veterans Affairs Research Communications) In-person social contact seems to offer some protection against depression and PTSD symptoms, but the same is not true of contact on Facebook, suggests a study by Veterans Affairs researchers and colleagues.

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