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EurekAlert! - Medicine and Health

10/16/2018 12:00 AM
For-profit nursing home residents more likely to be diagnosed with neglect issues
(University of Illinois at Chicago) Residents receiving care in for-profit nursing homes are almost twice as likely to experience health issues caused by substandard care compared with clients living in not-for-profit facilities or in homes in the community, according to a new report in the journal Gerontology.

10/16/2018 12:00 AM
Multidisciplinary team to develop stem cell-based approaches to restore vision
(University of Pennsylvania) Gene therapies have had success in treating blindness but can't save areas of the retina where cells have already died. In a new effort, University of Pennsylvania scientists John Wolfe, also of CHOP, and William Beltran, along with David Gamm of the University of Wisconsin-Madison, will attempt to develop a stem-cell-based approach that restores vision.

10/16/2018 12:00 AM
In the fight against Alzheimer's, Down syndrome may hold vital clues
(Arizona State University) In new research, Antonella Caccamo and her colleagues explore a number of critical factors that appear to link the Down syndrome (DS) and Alzheimer's disease. In a new project, Caccamo will use DS as a window into the underlying mechanisms that may give rise to Alzheimer's pathology. Using this complementary approach, her $3.1 million NIH grant will explore the effects of a critical protein complex known as mTOR.

10/16/2018 12:00 AM
New scholars named by program to promote research into the influence of gender on health
(University of Pennsylvania) The University of Pennsylvania's Melanie Kornides, Jennifer Lewey, and C. Alix Timko, also of the Children's Hospital of Philadelphia, are pursuing research that examines the role of sex and gender on health. The work is supported by the Building Interdisciplinary Research Careers in Women's Health program.

10/16/2018 12:00 AM
What makes a good life in late life? Citizenship and justice in aging societies
(The Hastings Center) A new Hastings Center Special Report calls on bioethics to 'broaden its lens' to improve the experience of aging and tackle problems of injustice affecting older adults and caregivers.

10/16/2018 12:00 AM
Why heart contractions are weaker in those with hypertrophic cardiomyopathy
(McGill University) Familial hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease in the US and affects an estimated 1 in 500 people around the world. A protein called myosin acts as the molecular motor which makes the muscles in the heart contract. An international team has discovered that in transgenic rabbits with the R403Q mutation,, individual myosin molecules and myofibrils (the basic rod-like filaments inside muscles) produce less force and a lower maximum velocity of contraction than those isolated from healthy hearts.

10/16/2018 12:00 AM
Hippocampus yields clues to treatment strategies for cognitive deficits in MS
(Kessler Foundation) 'Recent advances in neuroimaging have greatly improved our understanding of the involvement of the hippocampus in MS,' said John DeLuca, PhD, at Kessler Foundation. 'Now we are aware of subregions with different levels of susceptibility to damage, for example, and the potential for hippocampal plasticity and neurogenesis. The challenge is to correlate these findings with clinical manifestations and renew our efforts toward improving outcomes for the population with MS.'

10/16/2018 12:00 AM
Heroin vaccine technology advances as researchers are awarded grant for further testing
(The U.S. Military HIV Research Program (MHRP)) Researchers at the U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research (WRAIR) and SUNY Upstate Medical University in Syracuse, N.Y., have been awarded a grant to advance an experimental heroin vaccine through Phase I/IIa clinical trials to assess both its safety and its efficacy against a morphine challenge.

10/16/2018 12:00 AM
Video monitoring of tuberculosis treatment effective in urban and rural areas
(University of California - San Diego) Researchers from University of California San Diego School of Medicine, with statewide collaborators, report that patients who recorded videos of themselves taking tuberculosis (TB) medications better adhered to treatment than patients who were observed in-person.

10/16/2018 12:00 AM
Automated system identifies dense tissue, a risk factor for breast cancer, in mammograms
(Massachusetts Institute of Technology) Researchers from MIT and Massachusetts General Hospital have developed an automated model that assesses dense breast tissue in mammograms -- which is an independent risk factor for breast cancer -- as reliably as expert radiologists. This marks the first time a deep-learning model of its kind has successfully been used in a clinic on real patients, according to the researchers. With broad implementation, the researchers hope the model can help bring greater reliability to breast density assessments across the nation.

10/16/2018 12:00 AM
Perinatal women in RI to have increased access to behavioral health screenings
(Care New England ) Toward ensuring that pregnant and postpartum women are properly screened, the Health Resources and Services Administration (HRSA) has recently awarded the RI Department of Health a five year, $650,000 per year grant in partnership with the Center for Women's Behavioral Health at Women & Infants Hospital.

10/16/2018 12:00 AM
Age-related increase in estrogen may cause common men's hernia
(Northwestern University) An age-related increase in estrogen may be the culprit behind inguinal hernias, a condition common among elderly men that often requires corrective surgery. Men could be treated with hormone inhibitor to strengthen muscle, the researcher suggests.

10/16/2018 12:00 AM
No sweat required: UToledo finds hypertension treatment that mimics effect of exercise
(University of Toledo) By studying a chemical produced predominately in the liver, hypertension researchers at The University of Toledo have found a novel approach to lower blood pressure, even without reducing sodium intake or increasing exercise.

10/16/2018 12:00 AM
Simple stickers may save lives of patients, athletes and lower medical costs
(Purdue University) Purdue University researchers have created wearable medical electronic devices that someone can easily attach to their skin. The devices are made out of paper to lower the cost of personalized medicine.

10/16/2018 12:00 AM
UTA awarded US/international patents on material that attacks multiple cancers
(University of Texas at Arlington) The University of Texas at Arlington has been awarded U.S. and international patents on a nanoparticle material that can be activated by light, microwave, X-ray, or ultrasound to kill multiple kinds of cancers.

10/16/2018 12:00 AM
Environmental factors may trigger onset of multiple sclerosis
(American Friends of Tel Aviv University) A new Tel Aviv University study finds that certain environmental conditions like salt concentrations and temperature may precipitate structural changes that take place in myelin sheaths in the onset of multiple sclerosis (MS). Myelin sheaths are the 'insulating tape' surrounding axons; axons carry electrical impulses in neurons.

10/16/2018 12:00 AM
A human brain model in a petri dish?
(Case Western Reserve University) Researchers are now able to investigate the structural, cellular, and developmental intricacies of the human brain using bioengineered stem cell-based models called organoids. But ethics to help guide researchers and regulators lag behind the technological capability to 'grow' brains. A group of bioethicists and scientists will chart unexplored territory of neuroethics in a study called "The Brainstorm Project," led by Insoo Hyun, Ph.D.

10/16/2018 12:00 AM
Religious leaders' support may be key to modern contraception
(Johns Hopkins University Bloomberg School of Public Health) Women in Nigeria whose clerics extol the benefits of family planning were significantly more likely to adopt modern contraceptive methods, new research suggests, highlighting the importance of engaging religious leaders to help increase the country's stubbornly low uptake of family planning services.

10/16/2018 12:00 AM
Number of Veterans Affairs facilities offering acupuncture growing rapidly
(Mary Ann Liebert, Inc./Genetic Engineering News) Acupuncture is an increasingly important and effective component of chronic pain management and other areas of care in the Veterans Health Administration (VHA).

10/16/2018 12:00 AM
Mapping genetic differences in breast cancer can improve care for underserved populations
(University of Chicago Medical Center) A new study comparing DNA and RNA data from Nigerian breast cancer patients to patients in a United States database found that aggressive molecular features were far more prevalent in tumors from women of African ancestry than women of European ancestry. Those differences could explain disparities in breast cancer mortality for black women across the African Diaspora and hasten a shift to precisely targeted therapies.

10/16/2018 12:00 AM
Early onset of menopause and diabetes may limit life span
(The North American Menopause Society (NAMS)) Only in science fiction novels can scientists predict people's lifespans. However, researchers have advanced the understanding of those risk factors that adversely affect mortality rates. A new study concludes that women who experienced early menopause lived shorter lives and spent fewer years without diabetes than women who experienced normal or late menopause. Study results are published online in Menopause, the journal of The North American Menopause Society (NAMS).

10/16/2018 12:00 AM
Infectious diarrhea spores survive high temperatures of hospital laundering
(Society for Healthcare Epidemiology of America) Washing contaminated hospital bedsheets in a commercial washing machine with industrial detergent at high disinfecting temperatures failed to remove all traces of Clostridium difficile (C. difficile), a bacteria that causes infectious diarrhea, suggesting that linens could be a source of infection among patients and even other hospitals, according to a study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

10/16/2018 12:00 AM
ESMO advocacy for patient-centred care takes on global dimension
(European Society for Medical Oncology) Supportive and palliative care should be an integral part of cancer treatment (ESMO Position Paper, 2017). To maintain the spotlight on the topic, on Friday, 19 October, a special session at the ESMO 2018 Congress will be dedicated to this subject and followed on Sunday by the formal recognition of 20 newly-accredited Designated Centres of Integrated Oncology and Palliative Care. For the first time, institutions from Japan, Denmark, Estonia and Qatar feature among the laureates.

10/16/2018 12:00 AM
Machine-learning driven findings uncover new cellular players in tumor microenvironment
(CytoReason) New findings presented today by CytoReason reveals possible new cellular players in the tumor microenvironment that could impact the treatment process for the most in-need patients -- those who have already failed to respond to ipilimumab (anti-CTLA4) immunotherapy. Once validated, the findings could point the way to improved strategies for the staging and ordering of key immunotherapies in refractory melanoma.

10/16/2018 12:00 AM
Moving location of fruit and vegetables can lead to 15 percent sales increase
(University of Warwick) Moving location of fruit and vegetables in shops can lead to 15 percent sales increase.Sales increased without any further messaging or marketing.Research suggests a simple 'nudge' can lead to healthier diets for young adults.Findings based on data collected between 2012-17 in a real University campus grocery store.

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