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EurekAlert! - Medicine and Health

06/19/2018 12:00 AM
Combining different malaria vaccines could reduce cases by 91 percent
(Imperial College London) Using two experimental anti-malarial vaccines, which work in different ways, can greatly reduce the number of malaria infections in animal studies.

06/19/2018 12:00 AM
Children's immune system could hold the key to preventing sepsis
(University of Sheffield) Scientists have identified the key response that children use to control infections.

06/19/2018 12:00 AM
Opioid dependence in patients with degenerative spondylolisthesis: More likely to occur before than after surgery
(Journal of Neurosurgery Publishing Group) Researchers investigated risk factors for the development of opioid dependence in patients undergoing surgery for degenerative spondylolisthesis (DS). They found that, overall, patients were more likely to have a dependency on opioid medications before surgery than afterward.

06/18/2018 12:00 AM
BPA can induce multigenerational effects on ability to communicate
(University of Missouri-Columbia) Past studies have shown that biparental care of offspring can be affected negatively when females and males are exposed to bisphenol A (BPA. In a study published today in the journal PLOS One, researchers at the University of Missouri found that mice pups whose grandparents had been exposed to BPA, had different vocalization patterns. This, in turn, could also affect the amount of parental care they received. Scientists believe results could have important relevance to humans.

06/18/2018 12:00 AM
Princeton scientists uncover a factor important for ZIKA Virus host species restriction
(Princeton University) In 2013 and 2015, devastating outbreaks of ZIKA captured world attention. The virus is often transmitted from wild animals -- probably non-human primates -- via mosquitos to humans. This is the first comprehensive study to investigate which mammal species may host the ZIKA virus (ZIKV). 'We systematically tested the ability of ZIKV to infect cells from humans, great apes, New World and Old World monkeys, and mice,' explained Princeton Professor Alexander Ploss.

06/18/2018 12:00 AM
IUPUI entrepreneurs seek to quantify pressure applied during manual therapy
(Indiana University) Researcher-entrepreneurs Terry Loghmani, Sohel Anwar and Stanley Chien of IUPUI have developed an instrument system called Quantifiable Soft Tissue Manipulation. QSTM integrates an accelerometer, force sensors, a gyroscope and software to compute the force and motion parameters during manual therapy to treat soft-tissue injuries. The information can be displayed on a laptop computer or a tablet for real-time monitoring and recording of relevant data.

06/18/2018 12:00 AM
Often overlooked glial cell is key to learning and memory
(University of California - Riverside) Glial cells surround neurons and provide support -- not unlike hospital staff and nurses supporting doctors to keep operations running smoothly. These often-overlooked cells, which include oligodendrocytes and astrocytes, are the most abundant cell types in the central nervous system. But these cells do more than support neurons. They also actively influence them, University of California, Riverside, researchers report.

06/18/2018 12:00 AM
Better implants key to repair damaged knees
(Stellenbosch University) People whose knees have been affected by osteoarthritis, also known as the 'wear and tear' arthritis, often have to get knee implants to repair the damage. But if a knee implant does not fit the specific individual, it could lead to soft tissue damage, collapsing of the underlying bone, loosening of the implant and an increased likelihood of joint pain after an operation. One possible solution is to design implants that are patient-specific, anatomically accurate, reproduce normal knee motion and are ultimately repeatable.

06/18/2018 12:00 AM
The force is strong within us: New study explores cell mechanics at work
(Arizona State University) An ASU research team focused on measuring the stiffness, bending, twisting and viscosity of individual cells -- focused on a breast cancer cell line -- using all of the most state-of-the art technology at their disposal. How both healthy and cancerous cells respond to this environment -- and whether there are key differences that can be identified for future diagnostic applications was of keen interest to both the NCI and the physicists taking on the NCI's challenge.

06/18/2018 12:00 AM
Studying the brain at work: Drexel to host International Neuroergonomics Conference
(Drexel University) More than 100 experts will convene to discuss the emerging field of research, which aims to design systems for safer, more efficient operations and to advance the understanding of the relationship between the brain and everyday human tasks.

06/18/2018 12:00 AM
Purdue phoneme project creates new haptic communications future
(Purdue University) Communication could step beyond reading a cellular phone screen with a new technique by Purdue College of Engineering researchers to learn and read messages through a person's sense of touch.

06/18/2018 12:00 AM
AcuraStem receives fast-track SBIR grant
(AcuraStem, Inc.) AcuraStem, a fast-growing and innovative biotech company located in Monrovia, California, has been awarded a 3.7 million dollar Small Business Innovation Research (SBIR) Fast-Track grant (#R44NS105156) by the National Institute of Neurological Disorders and Stroke (NINDS) to continue research for the development of a small molecule therapeutic, 'AS2015', focused on treating patients with the genetic form of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) caused by expansion repeats in the gene C9ORF72.

06/18/2018 12:00 AM
Carbon nanotube optics provide optical-based quantum cryptography and quantum computing
(DOE/Los Alamos National Laboratory) Researchers at Los Alamos and partners in France and Germany are exploring the enhanced potential of carbon nanotubes as single-photon emitters for quantum information processing. Their analysis of progress in the field is published in this week's edition of the journal Nature Materials.

06/18/2018 12:00 AM
New asthma tool determines best treatment for severe asthma patients
(American College of Chest Physicians) To help enable stronger communication and understanding between the clinician and patient, the CHEST Foundation, the charitable foundation of the American College of Chest Physicians, Allergy & Asthma Network and American College of Allergy, Asthma & Immunology (ACAAI) have partnered to launch a new digital, interactive Shared Decision Making Tool.

06/18/2018 12:00 AM
CHEST® partners with Medscape to launch the moderate to severe asthma center of excellence
(American College of Chest Physicians) The American College of Chest Physicians (CHEST) announces a new partnership with Medscape focused on supporting physicians in addressing the challenges of diagnosing and treating moderate to severe asthma.

06/18/2018 12:00 AM
Unique immune-focused AI model creates largest library of inter-cellular communications
(CytoReason) New data published in Nature Biotech, represents the largest ever analysis of immune cell signaling research, mapping more than 3,000 previously unlisted cellular interactions, and yielding the first ever immune-centric modular classification of diseases. These data serve to rewrite the reference book on immune-focused inter-cellular communications and disease relationships.New Data Published by Nature Biotechnology: Covering 16,000,000 scientific articles, this massive Natural Language Processing (NLP) project quadruples the reference body of organized inter-cellular signalling interactions, plots inter-cellular immune profiles for 188 diseases and creates the first ever immune-centered map of disease similarities and differences.

06/18/2018 12:00 AM
Targeting the engine room of the cancer cell
(Columbia University Irving Medical Center) Researchers at Columbia University Irving Medical Center (CUIMC) have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug combinations that are most likely to kill them.

06/18/2018 12:00 AM
Plant-based diets improve cardiometabolic risk factors in diabetes patients
(Physicians Committee for Responsible Medicine) New review in the journal Clinical Nutrition finds that plant-based diets improve cardiometabolic risk factors in those with type 2 diabetes.

06/18/2018 12:00 AM
Novel information about the effects of in vitro fertilization on embryonic growth
(University of Helsinki) In vitro fertilization affects the regulatory region of genes essential for placental and embryonic growth, as well as the birth weight. A new study suggests that the effects depend on genetic variation inherited from the parents. This information could be useful in development of assisted reproduction technologies.

06/18/2018 12:00 AM
Risky opioid prescriptions linked to higher chance of death
(RAND Corporation) Most people who misuse opioids are first exposed to the drugs through prescriptions so improving prescribing is targeted as one way to help curb the nation's opioid abuse epidemic. A new study identified six types of risky opioid prescriptions and found that all were linked to a higher chance of death, including fatal opioid overdoses. The study found more than 6 percent of Massachusetts adults received a risky opioid prescription during a five-year period.

06/18/2018 12:00 AM
Insilico to present latest advances in Machine Learning & Artificial Intelligence for drug discovery
(InSilico Medicine, Inc.) Insilico Medicine presents at the Advanced Machine Learning and Artificial Intelligence for Drug Discovery & Development Conference, organized by BIS Group. The presentation will focus on the application of Generative Adversarial Networks (GANs) for generation of novel small organic molecules with the desired set of pharmacological properties.

06/18/2018 12:00 AM
Neuroscientists map brain's response to cold touch
(Carnegie Mellon University) Carnegie Mellon neuroscientists have mapped the feeling of cool touch to the brain's insula in a mouse model. The findings provide an experimental model that will advance research into conditions like pain and hypersensitivity to cold and help researchers to continue to unravel the multifaceted ways touch is represented in the brain.

06/18/2018 12:00 AM
New method to preserve boy cancer patient fertility being developed at Ben-gurion U.
(American Associates, Ben-Gurion University of the Negev) "Our results demonstrate, for the first time, the presence of biologically active SPGCs in testicular biopsies of chemotherapy-treated PCPBs, and their capacity to develop in vitro to different stages of spermatogenesis, including the generation of sperm-like cells," according to lead researcher Prof. Mahmoud Huleihel, a member of BGU's Shraga Segal Department of Microbiology, Immunology and Genetics. "This study may open the way for new therapeutic strategies for fertility preservation of PCPBs and for azoospermic patients."

06/18/2018 12:00 AM
Reducing the risk of dementia through lifestyle changes
(Baycrest Centre for Geriatric Care) Canadian researchers are recruiting older adults across Toronto and Montreal to explore the benefits of different types of brain training and lifestyle interventions for two clinical trials.

06/18/2018 12:00 AM
Compilation of research discussed at the Global Forum On Nicotine: Warsaw, June 16, 2018
(Abzed) Below is a summary of the new and recent research discussed at this conference.

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